CRM-AZA-Mus

Mussel Tissue Certified Reference Material for Azaspiracids

Azaspiracids (AZAs) are a group of marine biotoxins containing both carboxyl and amine functional

groups (Figure 1). AZAs are produced by the small dinoflagellate Azadinium spinosum [1] and have

been shown to accumulate to high levels in a variety of shellfish species [2]. Human consumption of

shellfish contaminated with AZAs causes poisoning with symptoms resembling those of diarrhetic

shellfish poisoning [3]. The maximum permissible total level of AZA1, -2 and -3 in shellfish is currently

0.16 mg/kg in whole tissue [4]. CRM-AZA-Mus is a certified reference material (CRM) prepared from

naturally contaminated mussel tissues (Mytilus edulis) containing certified concentrations of AZA1, -2

and -3 (Table 1). CRM-AZA-Mus is designed to assist the analyst in assessing entire analytical

methods used to monitor AZA toxins in shellfish tissues. Each bottle contains approximately 8 g of

mussel homogenate with AZAs at levels appropriate for analytical testing.

Expiry date: 1 year from date of sale.

Storage conditions: -12 ?C or below

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