CRM-AZA3

Certified Calibration Solution for Azaspiracid-3

Azaspiracids (AZAs) are a class of shellfish toxins first discovered in Ireland in 1995 after a human

intoxication event linked to the consumption of shellfish [1,2]. AZAs possess unique spiro assemblies

with both carboxyl and amine moieties [3,4]. The origin of AZAs has been identified as the

dinoflagellate Azadinium spinosum [5]. Intoxication symptoms can include nausea, stomach cramps,

headache, vomiting and diarrhea. The maximum permissible total level of AZAs (AZA1, AZA2, and

AZA3) in shellfish is currently 0.16 mg/kg in whole tissue [6]. CRM-AZA3-b is a certified calibration

solution of AZA3 in methanol and is a replacement for CRM-AZA3, which was released in 2011.

Azaspiracid-3

CAS registry No.: 265996-93-8

Molecular formula: C 46 H 69 NO 12

Formula molecular weight: 828.05 g/mol

[M+H] + : monoisotopic mass: 828.4893 Da

Period of validity: 1 year from date of sale

Storage conditions: -12 °C or below

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