CRM-AZA1

Certified Calibration Solution for Azaspiracid-1

Azaspiracids (AZAs) are a potent class of shellfish toxins first discovered in Ireland in 1995 after a

human intoxication event linked to the consumption of shellfish [1,2]. AZA1 possesses unique spiro

assemblies with both carboxyl and amine moieties [3,4]. The origin of AZAs has been identified as the dinoflagellate Azadinium spinosum [5]. Intoxication symptoms can include nausea, stomach cramps, headache, vomiting and diarrhea. The maximum permissible total level of AZAs (AZA1, AZA2, and AZA3) in shellfish is currently 0.16 mg/kg in whole tissue [6]. CRM-AZA1-b is a certified calibration solution of AZA1 in methanol and is a replacement for CRM-AZA1, which was released in 2007.

Azaspiracid-1

CAS registry No.: 214899-21-5

Molecular formula: C 47 H 71 NO 12

Molecular weight: 842.1

[M+H] + : m/z 842.5049

Period of validity: 1 year from date of sale

Storage conditions: -12 °C or below

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