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Product Uses

• Study inhibitors of SOS1 GTP exchange activity

• Identification of SOS1 binding proteins

• Study of SOS1 GEF activity with different GTPases

Materials

The human SOS1 exchange domain (564-1049) protein (SOS1-ExD) has been produced in a bacterial expression system. The recombinant protein contains a 6 histidine tag (His-tag) at its amino terminus. The approximate molecular weight of the SOS1-ExD protein is 61 kDa. The protein is supplied as a lyophilized white powder.