Product Uses

• Study of G12V K-Ras4B exchange activity with different GEFs

• Identification of G12V K-Ras4B exchange factors (GEFs)

• Positive control for GEF studies

• Biochemical characterization of G12V K-Ras4B protein interactions

• Western blot standard

Materials

The G12V (glycine to valine at amino acid position 12) mutant human K-Ras4B protein has been produced in a bacterial expression system. The recombinant protein contains six histidine residues at its amino terminus (His-tag). The molecular weight of 6xHis tagged G12V K-Ras4B is approximately 25 kDa and it is supplied as a white lyophilized powder.